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at the Dorsetshire Assize, the chief baron and many lawyers were killed by it. The High Sheriff of Somerset also took the disease and died. A single Scotch regiment, being infected from some prisoners, lost no less than two hundred. In 1750 the disease was so virulent at Newgate, in the heart of London, that two judges, the lord mayor, sundry aldermen, and many others, died of it. It is worth noting that, while efforts at sanitary dealing with this state of things were few, the theological spirit developed a new and special form of prayer for the sufferers and placed it in the Irish Prayer Book. These forms of prayer seem to have been the main reliance through the first half of the eighteenth century. But about 1750 began the work of John Howard, who visited the prisons of England, made known their condition to the world, and never rested until they were greatly improved. Then he applied the same benevolent activity to prisons in other countries, in the far East, and in southern Europe, and finally laid down his life, a victim to disease contracted on one of his missions of mercy; but the hygienic reforms he began were developed more and more until this fearful blot upon modern civilization was removed.(335) (335) For Erasmus, see the letter cited in Bascome, History of Epidemic Pestilences, London, 1851. For the account of the condition of Queen Elizabeth's presence chamber, see the same, p. 206; see also the same for attempts at sanitation by Caius, Mead, Pringle, and others; also see Baas and various medical authorities. For the plague in London, see Green's History of the English People, chap. ix, sec. 2; and for a more detailed account, see Lingard, History of England, enlarged edition of